methyl (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoate
Carbidopa impurity E
CAS: 52514-63-3
Molecular Formula: C11H16N2O4
methyl (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoate - Names and Identifiers
methyl (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoate - Physico-chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molar Mass | 240.26 |
methyl (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoate - Introduction
Carbidopa impurity E is a common organic compound with the chemical formula C8H9NO2. It is also known as 2-amino-4-methoxyphenol. The following is a detailed description of the nature, use, formulation and safety information of Carbidopa impurity E:
Nature:
-Appearance: Carbidopa impurity E is white crystalline or crystalline powder.
-Solubility: It is insoluble in water, but soluble in alcohol, ether and benzene and other organic solvents.
-Melting point: The melting point of Carbidopa impurity E is about 153-156 degrees Celsius.
Use:
- Carbidopa impurity E is commonly used as an intermediate in drug synthesis. It is involved in the synthesis of some drugs, such as the preparation of carbidopa.
-It can also be used as an organic chemical reagent, a catalyst or reagent for some organic reactions.
Preparation Method:
The preparation method of Carbidopa impurity E can be carried out through the following steps:
1. P-cresol reacts with iodine under alkaline conditions to generate iodocresol.
2. Iodocresol is used to react with acetone to generate disubstituted ketones through keto-alcohol interconversion reaction.
3. Finally, the ketone is reacted with the alkaline esterifying agent of anhydrous acetic acid to generate Carbidopa impurity E.
Safety Information:
Carbidopa impurity E has low toxicity under normal conditions, but the following safety precautions still need to be paid attention:
-It is an organic compound and should be avoided from prolonged contact with the skin or inhalation of its dust.
-During use, wear appropriate protective gloves and glasses.
-If taken by mistake or inhaled by mistake, please seek medical attention and provide the correct name and chemical formula of the drug for the doctor's reference.
Nature:
-Appearance: Carbidopa impurity E is white crystalline or crystalline powder.
-Solubility: It is insoluble in water, but soluble in alcohol, ether and benzene and other organic solvents.
-Melting point: The melting point of Carbidopa impurity E is about 153-156 degrees Celsius.
Use:
- Carbidopa impurity E is commonly used as an intermediate in drug synthesis. It is involved in the synthesis of some drugs, such as the preparation of carbidopa.
-It can also be used as an organic chemical reagent, a catalyst or reagent for some organic reactions.
Preparation Method:
The preparation method of Carbidopa impurity E can be carried out through the following steps:
1. P-cresol reacts with iodine under alkaline conditions to generate iodocresol.
2. Iodocresol is used to react with acetone to generate disubstituted ketones through keto-alcohol interconversion reaction.
3. Finally, the ketone is reacted with the alkaline esterifying agent of anhydrous acetic acid to generate Carbidopa impurity E.
Safety Information:
Carbidopa impurity E has low toxicity under normal conditions, but the following safety precautions still need to be paid attention:
-It is an organic compound and should be avoided from prolonged contact with the skin or inhalation of its dust.
-During use, wear appropriate protective gloves and glasses.
-If taken by mistake or inhaled by mistake, please seek medical attention and provide the correct name and chemical formula of the drug for the doctor's reference.
Last Update：2024-04-09 21:00:56
Supplier List
Spot supply
Product Name: Carbidopa Impurity 5（Carbidopa EP Impurity E） Visit Supplier Webpage Request for quotationCAS: 52514-63-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Carbidopa Impurity 5（Carbidopa EP Impurity E） Visit Supplier Webpage Request for quotationCAS: 52514-63-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
View History